It is VERY IMPORTANT to note that the key in understanding calcium supplementation is to understand that the most important factor is the amount of elemental calcium absorbed. Each suppository delivers 136mgs of elemental Calcium. This is the equivalent of six (6) 500 mg calcium citrate capsules or tablets. This is because calcium citrate is approximately 78-80% citric acid. Therefore in one capsule there is really 100mgs of calcium. Further, because of absorption issues, that often results in 20-25 mgs being absorbed by the body. Most healthcare professionals are profoundly unaware of this fact. Therefore the recommendation of oral 1000mgs of calcium citrate by medical professionals – is ONLY 40 mgs of absorbed elemental calcium – less than 1/10 of what is needed on a daily basis. THEREFORE, the suppository delivery of calcium offers a viable alternative for persons who need adequate amounts of calcium to meet their healthcare need.
Both calcium and magnesium are essential to healthy and productive physiological well being. The calcium and magnesium suppository provides the RDA levels of elemental calcium in the most bioactive forms that go directly into the cells. Magnesium deficiency has an effect on the absorption and release of calcium and calcium is crucial to physical well being. One example is that when the cells have enough calcium, the blood may have a deficiency and low blood calcium is a known consequence of magnesium deficiency. The Calcium and Magnesium suppository provides a person with the essential amounts of elemental calcium and is the most effective solution for individuals that suffer from poor and/or inadequate intestinal absorption of calcium.
Why Calcium and Magnesium should be taken together in the same supplement.
You do not need to take magnesium and calcium together in the same supplement to absorb calcium. The confusion arises from misunderstanding the difference between metabolism and absorption. The body needs magnesium to PROPERLY USE CALCIUM, IN OTHER WORDS TO METABOLIZE CALCIUM. But this has to do with what happens to calcium after it has been absorbed, not with calcium absorption itself. However, with that understood there is no doubt that Magnesium is a crucially important essential mineral. Magnesium plays many roles in human physiology, including calcium metabolism. Magnesium deficiency impairs secretion of PTH (parathyroid hormone) and that hormone increases absorption of calcium in the gut by activating vitamin D3. The Parathyroid Hormone also triggers release of calcium from the bone when the blood levels of calcium fall too low to meet the body’s physiological calcium requirements. At the same time, activation of vitamin D3 requires magnesium, because the enzyme that catalyzes this activation needs magnesium to work.
Calcium is important for cellular functions, but excess calcium inside the cell can be harmful. Magnesium prevents excess calcium from accumulating inside cells. Interestingly, when cells contain too much calcium, the blood may not have enough. Low blood calcium, know as “hypocalcemia,” is a known consequence of magnesium deficiency. So the importance of magnesium cannot be understated. The bottom line is that we need magnesium to make proper use of calcium. In fact, taking calcium supplements may increase the need for magnesium by increasing the proportional intake of calcium relative to magnesium. Many people, especially seniors, consume less than the RDI, as shown in nutritional surveys. Therefore when taking 1000 mg or more of elemental calcium via diet or calcium in supplements, as is widely recommended, without magnesium the calcium to magnesium ratio may become imbalanced and therefore magnesium is included to maintain the optimal ratio.
1. Paunier, L. Effect of magnesium on phosphorus and calcium metabolism. Montasschr Kinderheilkd 1992; 140(Suppl): S17-S20.
2. Cashman, K. Optimal nutrition: calcium, magnesium and phosphorus. Proceedings of the Nutrition Society 1999; 58:477-87.
3. Morgan, K.E.A., Magnesium and calcium dietary intakes of the U.S. population. Journal of the American College of Nutrition, 1985. p. 195-206.
4. Celotti, F. Bignamini, A. Dietary calcium and mineral/vitamin supplementation: a controversial problem. The Journal of International Medicinal Research 1999; 27:1-14.
Each Zetpil™ Calcium/Magnesium contains a proprietary blend of the following: highly bioavailable forms of Calcium yielding 160 mg Elemental Calcium; 200 mg of highly bioavailable forms of Magnesium yielding 40 mg of elemental Magnesium. Base The base is a proprietary combination of plant and fruit butters, vegetable acids, medium chain triglycerides, phospholipids, lecithin, vegetable starches, cellulose, oligosaccharides derivatives, polysaccharides and cycloamylose derivatives.
Recommended use: 2-3 Calcium/Magnesium per day or as directed by your health care professional.
If you choose to use this product as a rectal suppository, it is highly recommended you attempt to clear your bowels prior to inserting it to avoid premature evacuation. To facilitate insertion it is recommended you moisten the product by passing it under a stream of cool water or use a personal lubricant. When used as a suppository, this product requires 15-20 minutes retention to ensure the complete absorption of the bioactive ingredients. This suppository can be inserted in any position. Although not required, if inserted while lying on one’s side, consider remaining in the supine position for 1-3 minutes following insertion.(Always insert flat end of suppository first).
- Although safe for children, this product should be kept out of the reach of children.
- Do not use if the suppositories are open or damaged.
- As with any nutrient if you are pregnant or breastfeeding, seek the advice of a health care provider before using this product.
This product contains an extract from soybeans. This product is contraindicated in individuals with a known hypersensitivity to phospholipids, sesame seed oils or any of the ingredients and should avoid taking this product.
Individuals that have chosen to take this product as part of a personal nutrient program have overwhelmingly chosen to utilize this product as a rectal suppository or as a vaginal pessary. However, this product can also be taken safely by mouth. If one chooses to take this product orally, then this product may be considered a dietary supplement in accordance with current FDA guidelines.
Disclaimer: These statements have not been evaluated by the FDA This product is a Federal Food, Drug, and Cosmetic Act compliant combination of naturally derived FDA GRAS (Generally regarded As Safe) herbal, nutraceutical, vitamins, minerals and amino acids products legally sold in the USA. In accordance with FDA regulations, when taken orally, this product may be considered a dietary supplement as defined by section 201(ff) of the Act, 21 U.S.C. § 321(ff). Also, this product consists ONLY of a combination of naturally derived FDA GRAS (Generally regarded As Safe) herbal, nutraceutical, vitamins, minerals and amino acids products legally sold in the USA. Therefore, this product cannot be considered a drug as defined in section 201(g)(1) of the Act, 21 U.S.C. § 321(g)(1). This product is not intended to affect the structure or function of the body and is not intended for use in the diagnosis, cure, mitigation, treatment or prevention of disease in man. Any nutritional suggestions and research regarding this product are provided for informational purposes only, and are not intended to diagnose, treat, cure or prevent disease nor should any information provided be used as a substitute for sound medical advice.