Calcium/Magnesium w/Vitamin D3 and Cofactors
Both calcium and magnesium are essential to healthy and productive physiological well being. The calcium and magnesium suppository provides the RDA levels of elemental calcium in the most bioactive forms that go directly into the cells. Magnesium deficiency has an effect on the absorption and release of calcium and calcium is crucial to physical well being. One example is that when the cells have enough calcium, the blood may have a deficiency and low blood calcium is a known consequence of magnesium deficiency. The Calcium and Magnesium suppository provides a person with the essential amounts of elemental calcium and is the most effective solution for individuals that suffer from poor and/or inadequate intestinal absorption of calcium.
Why Calcium and Magnesium should be taken together in the same supplement.
You do not need to take magnesium and calcium together in the same supplement to absorb calcium. The confusion arises from misunderstanding the difference between metabolism and absorption. The body needs magnesium to PROPERLY USE CALCIUM, IN OTHER WORDS TO METABOLIZE CALCIUM. But this has to do with what happens to calcium after it has been absorbed, not with calcium absorption itself.  However, with that understood there is no doubt that Magnesium is a crucially important essential mineral. Magnesium plays many roles in human physiology, including calcium metabolism. Magnesium deficiency impairs secretion of PTH (parathyroid hormone) and that hormone increases absorption of calcium in the gut by activating vitamin D3. The Parathyroid Hormone also triggers release of calcium from the bone when the blood levels of calcium fall too low to meet the body's physiological calcium requirements. At the same time, activation of vitamin D3 requires magnesium, because the enzyme that catalyzes this activation needs magnesium to work.
Calcium is important for cellular
functions, but excess calcium inside the cell can be harmful. Magnesium
prevents excess calcium from accumulating inside cells. Interestingly,
when cells contain too much calcium, the blood may not have enough. Low
blood calcium, know as "hypocalcemia," is a known consequence of
magnesium deficiency.  So the importance of magnesium cannot be
understated. The bottom line is that we need magnesium to make proper
use of calcium. In fact, taking calcium supplements may increase the
need for magnesium by increasing the proportional intake of calcium
relative to magnesium. Many people, especially seniors, consume less
than the RDI, as shown in nutritional surveys. Therefore when taking
1000 mg or more of elemental calcium via diet or calcium in supplements,
as is widely recommended, without magnesium the calcium to magnesium
ratio may become imbalanced and therefore magnesium is included to
maintain the optimal ratio.
1. Paunier, L. Effect of magnesium on phosphorus and calcium metabolism. Montasschr Kinderheilkd 1992; 140(Suppl): S17-S20.
2. Cashman, K. Optimal nutrition: calcium, magnesium and phosphorus. Proceedings of the Nutrition Society 1999; 58:477-87.
3. Morgan, K.E.A., Magnesium and calcium dietary intakes of the U.S. population. Journal of the American College of Nutrition, 1985. 4: p. 195-206.
4. Celotti, F. Bignamini, A. Dietary calcium and mineral/vitamin supplementation: a controversial problem. The Journal of International Medicinal Research 1999; 27:1-14.
Each Zetpil™ OsteoCalcium/Magnesium
PLUS with Vitamin D suppository contains a proprietary blend of the
following: highly bioavailable forms of Calcium yielding 160 mg
Elemental Calcium; 200 mg of highly bioavailable forms of Magnesium
yielding 40 mg of elemental Magnesium; Vitamin D3 1000 iu.; Vitamin K1
60 mcg. Suppository Base The base is a proprietary combination of
plant and fruit butters, medium chain triglycerides, natural
phospholipids, lecithin, vegetable starches, guar gum and xanthan gum.
Recommended use: 2 to 3 suppositories per day or as directed by your health care professional.
This product contains an extract from soybeans. This product contains NO milk, egg, fish, peanuts, crustacean (lobster, crab, shrimp), tree nuts, wheat, yeast, gluten, corn, rice, sugar, preservatives or hydrogenated oils.